Case report: a 2-year-old with cerebral venous sinus thrombosis had both iron deficiency anaemia and high Lp(a) (Front Pediatr 2025)

This case report describes a two-year-old girl who developed cerebral venous sinus thrombosis (CVST), a rare but life-threatening condition in children, in the setting of both severe iron deficiency anaemia and elevated lipoprotein(a). The authors note that several prior case reports have separately linked CVST to severe iron deficiency anaemia, and that elevated Lp(a) is accepted by some authors as a thrombophilic risk factor, with the two factors correlated with increased frequency in several clinical reports. This case illustrates the co-occurrence of both risk factors in a single paediatric patient and supports considering Lp(a) measurement alongside iron studies when working up unexplained paediatric CVST.