Plaque imaging 64 items

Studies

• Inflammation, cholesterol, Lp(a) and 30-year cardiovascular outcomes in women (Ridker et al., NEJM 2024)N Engl J Med · December 2024 8
• Lp(a) and oxidised phospholipids drive valve calcification activity and progression in aortic stenosis (Zheng et al., JACC 2019)J Am Coll Cardiol · May 2019 8
• Oxidised phospholipids on Lp(a) drive arterial wall inflammation and a primed monocyte response (van der Valk et al., Circulation 2016)Circulation · August 2016 8
• First-degree relatives of people with elevated Lp(a) have more MACE: Swedish registry cohort (Kindborg et al., EHJ 2026)Eur Heart J · July 2026 7
• Coronary artery calcium still stratifies risk in people with elevated Lp(a): a four-cohort study (Bhatia et al., JACC 2026)J Am Coll Cardiol · May 2026 7
• High Lp(a) accelerates low-attenuation (necrotic core) plaque progression on serial CT angiography (Kaiser et al., JACC 2022)J Am Coll Cardiol · January 2022 7
• One-time LDL-C, hs-CRP and Lp(a) screening predicts 20-year events in European men and women: EPIC-Norfolk (Kraaijenhof, Nurmohamed et al., EHJ 2025)Eur Heart J · October 2025 6
• Lp(a) tracks focal vulnerable plaques, LDL-C tracks pancoronary plaque burden: PROSPECT II (Erlinge et al., JACC 2025)J Am Coll Cardiol · June 2025 6
• Elevated Lp(a) in 2.9 million Chinese adults and its association with multisite subclinical atherosclerosis (Man et al., JACC 2025)J Am Coll Cardiol · June 2025 6
• Lp(a) is associated with the onset but not the progression of aortic valve calcification: the Rotterdam Study (Kaiser et al., EHJ 2022)Eur Heart J · October 2022 6
• Lp(a) measurement issues: a mountain out of a molehill? (Kronenberg, Atherosclerosis 2022)Atherosclerosis · May 2022 6
• 2021 Canadian Cardiovascular Society dyslipidaemia guidelines: Lp(a) once in a lifetime (Pearson et al., Can J Cardiol 2021)Can J Cardiol · August 2021 6
• Lp(a) and dementia in 539,478 people: no association with Alzheimer's or vascular dementia on continuous scales (Thomas et al., EHJ 2025)Eur Heart J · November 2025 5
• Lp(a) raises coronary event risk mainly by driving plaque burden, SCAPIS cohort of 28,529 (JACC Cardiovasc Imaging 2026)JACC Cardiovasc Imaging · July 2026 8
• High-risk Lp(a) accelerates coronary plaque progression across CCTA, IVUS and OCT, meta-analysis of 19,822 (Atherosclerosis 2026)Atherosclerosis · March 2026 8
• Evolocumab stabilises coronary plaque more effectively in ACS patients with high Lp(a) than low, HUYGENS trial secondary analysis of OCT imaging finds (Eur J Prev Cardiol 2025)Eur J Prev Cardiol · April 2025 8
• Lp(a) link to carotid plaque is strongest in white participants and weaker in Black participants, the multi-ethnic MESA study of 5,155 adults (Arterioscler Thromb Vasc Biol 2019)Arterioscler Thromb Vasc Biol · March 2019 8
• Lp(a) predicts continued carotid plaque progression despite intensive LDL-lowering therapy, an AIM-HIGH trial imaging substudy of 152 patients (Arterioscler Thromb Vasc Biol 2018)Arterioscler Thromb Vasc Biol · January 2018 8
• Obstructive sleep apnea raises cardiovascular risk only in ACS patients with above-median Lp(a), OSA-ACS cohort of 1137 (Sleep 2026)Sleep · June 2026 7
• Lp(a) raises post-PCI cardiovascular risk mainly when pericoronary inflammation is high, machine-learning study (J Clin Lipidol 2026)J Clin Lipidol · June 2026 7
• Lp(a) uniquely predicts low-density noncalcified plaque beyond CAC and hsCRP, CCTA cohort of 547 (Eur Heart J Cardiovasc Imaging 2026)Eur Heart J Cardiovasc Imaging · April 2026 7
• Elevated Lp(a) predicts high-risk plaque features but not calcified volume, CCTA study of 3,642 individual plaques (Eur J Prev Cardiol 2026)Eur J Prev Cardiol · April 2026 7
• High Lp(a) tracks with advanced coronary calcium and carotid atherosclerosis in asymptomatic patients, cohort of 3,697 (Nutr Metab Cardiovasc Dis 2026)Nutr Metab Cardiovasc Dis · April 2026 7
• Lipoprotein(a), High-Sensitivity C-Reactive Protein, and Incident ASCVD Risk in Individuals Without Standard Modifiable Risk FactorsEur J Prev Cardiol · April 2026 7
• Lp(a) tracks with coronary plaque burden but not long-term mortality in established ASCVD, combined cohort of 798 (Eur J Prev Cardiol 2026)Eur J Prev Cardiol · March 2026 7
• Elevated Lp(a) marks a high-risk phenotype in advanced coronary calcification, IVUS study of 292 (Int J Cardiol Cardiovasc Risk Prev 2026)Int J Cardiol Cardiovasc Risk Prev · February 2026 7
• Elevated Lp(a) predicts higher baseline coronary plaque burden and faster low-attenuation plaque growth on serial CT angiography (Front Cardiovasc Med 2026)Front Cardiovasc Med · January 2026 7
• Rising Lp(a) independently predicts coronary plaque progression on serial IVUS despite aggressive statin therapy, in 79 CAD patients (Sci Rep 2025)Sci Rep · December 2025 7
• High Lp(a) drives greater fibrotic coronary plaque volume in men but not women on CT angiography, COPRODUCTION registry of 1,946 patients finds (Clin Res Cardiol 2025)Clin Res Cardiol · October 2025 7
• Combining Lp(a) with CT-quantified pericoronary fat inflammation sharpens MACE prediction in non-obstructive coronary disease, 1,052-patient study finds (Int J Cardiol 2026)Int J Cardiol · September 2025 7
• Elevated Lp(a) causes more diffuse coronary flow limitation, PIONEER IV substudy of 150 matched patients (Cardiovasc Revasc Med 2026)Cardiovasc Revasc Med · July 2025 7
• Elevated Lp(a) tracks with vulnerable intracranial plaque features on high-resolution MRI and a 2.65-fold higher stroke recurrence risk (Eur Radiol 2025)Eur Radiol · June 2025 7
• Adding Lp(a) to standard risk models improves coronary disease reclassification by up to 42% in patients without modifiable risk factors, BioHEART-CT study of 1,718 finds (Eur J Prev Cardiol 2025)Eur J Prev Cardiol · June 2025 7
• Elevated Lp(a) predicts higher baseline plaque burden and faster low-attenuation plaque growth in 1,694 diabetic patients on serial CT angiography (Eur Radiol 2025)Eur Radiol · February 2025 7
• Lp(a) concentration, not apo(a) isoform size, predicts angiographic coronary disease severity in 263 men (Atherosclerosis 2018)Atherosclerosis · June 2018 7
• Elevated Lp(a) predicts higher coronary calcium scores in healthy relatives of patients with premature heart disease, a study of 937 family members (J Clin Lipidol 2018)J Clin Lipidol · January 2018 7
• Lp(a) does not predict coronary plaque progression during intensive statin therapy, a SATURN substudy of 915 patients (Atherosclerosis 2017)Atherosclerosis · June 2017 7
• Lipoprotein apheresis improves myocardial perfusion and plaque burden in refractory angina patients with high Lp(a), a randomised crossover trial of 20 patients (Eur Heart J 2017)Eur Heart J · May 2017 7
• Lp(a) predicts carotid artery thickening only in HIV-infected young women, the Women's Interagency HIV Study of 250 participants (Arterioscler Thromb Vasc Biol 2017)Arterioscler Thromb Vasc Biol · March 2017 7
• Lp(a) predicts carotid stenosis and occlusion but not total plaque area, suggesting a thrombotic mechanism, a study of 876 patients (Arterioscler Thromb Vasc Biol 2008)Arterioscler Thromb Vasc Biol · July 2008 7
• Despite 2-3 times higher Lp(a), Black adults show no link between Lp(a) and coronary calcium, the Dallas Heart Study of 761 Black and 527 white adults (Circulation 2005)Circulation · March 2005 7
• Lp(a) impairs blood vessel function most strongly in African Americans, who have nearly 4 times higher levels than Caucasians, a multiethnic study of 89 people (J Am Coll Cardiol 2004)J Am Coll Cardiol · May 2004 7
• Association of elevated Lp(a) with vulnerable plaque features on coronary imaging: a meta-analysis (Int J Cardiol Heart Vasc 2026)Int J Cardiol Heart Vasc · September 2026 6
• Lp(a) levels remain unchanged despite LDL-C <55 mg/dL in polyvascular disease (J Am Heart Assoc 2026)J Am Heart Assoc · August 2026 6
• Coronary imaging reveals how Lp(a) drives plaque burden and high-risk morphology, review (Curr Atheroscler Rep 2026)Curr Atheroscler Rep · July 2026 6
• Lp(a) tracks non-calcified plaque in men but calcified plaque in women, 7201-person asymptomatic CCTA cohort (J Cardiol 2026)J Cardiol · July 2026 6
• Lp(a) above 18.8 mg/dL independently predicts coronary plaque vulnerability on IVUS, 292-patient study (J Atheroscler Thromb 2026)J Atheroscler Thromb · April 2026 6
• Hyperacute-phase Lp(a) predicts intracoronary thrombus, stable-phase Lp(a) predicts layered plaque, OCT study of 142 (Coron Artery Dis 2026)Coron Artery Dis · April 2026 6
• Lp(a) does not track with carotid thickness or stenosis despite its stroke-risk link, BIOSIGNAL cohort of 1,161 (Lipids Health Dis 2026)Lipids Health Dis · March 2026 6
• Elevated Lp(a) links to multivessel disease and high coronary calcium across two Spanish prevention cohorts of 1,043 (Am J Prev Cardiol 2026)Am J Prev Cardiol · January 2026 6
• Lp(a) tracks with subclinical coronary disease in low-risk ageing endurance athletes, but does not explain their higher CAD prevalence, Master@Heart study finds (Eur J Prev Cardiol 2025)Eur J Prev Cardiol · October 2025 6
• Imaging confirms Lp(a) drives high-risk coronary plaque features, from lipid-rich cores to thin fibrous caps, review synthesises (Rev Cardiovasc Med 2025)Rev Cardiovasc Med · October 2025 6
• Lp(a) of 30 mg/dL or above predicts faster growth of untreated ('non-culprit') plaques after ACS, OCT-based study of 177 patients finds (Catheter Cardiovasc Interv 2025)Catheter Cardiovasc Interv · May 2025 6
• Elevated Lp(a) independently predicts lipid-rich, vulnerable coronary plaque on OCT in 202 ACS patients (Catheter Cardiovasc Interv 2025)Catheter Cardiovasc Interv · December 2024 6
• Lp(a) rises stepwise with coronary vessel disease and abdominal, but not thoracic, aortic plaque, an MRI study of 143 patients (Atherosclerosis 2012)Atherosclerosis · February 2012 6
• Elevated Lp(a) does not thicken carotid arteries in healthy young adults, a study of 151 volunteers (Atherosclerosis 2007)Atherosclerosis · February 2006 6
• High Lp(a) blunts insulin-enhanced coronary blood flow in young healthy men, a PET imaging study of 30 men (Atherosclerosis 2005)Atherosclerosis · December 2004 6
• Lp(a) does not correlate with coronary calcium in asymptomatic postmenopausal women, a study of 178 women (J Am Coll Cardiol 2000)J Am Coll Cardiol · February 2000 6
• Imaging for subclinical atherosclerosis aids risk stratification in patients with elevated Lp(a) (J Clin Lipidol 2026)J Clin Lipidol · September 2026 5
• Markedly elevated Lp(a) unmasks vulnerable plaque missed by a zero calcium score, case report in sarcoidosis (J Clin Lipidol 2026)J Clin Lipidol · June 2026 5
• Association of Elevated Lipoprotein(a) and Diabetes Mellitus With Survival Outcomes in Patients With Coronary Artery Disease: Findings From the CIN-II and RED-CARPET CohortsDiabetes Obes Metab · February 2026 5
• Higher Lp(a) predicts carotid plaque ulceration on angiography in patients considered for carotid revascularisation (J Atheroscler Thromb 2026)J Atheroscler Thromb · August 2025 5
• Clinical value of Lipoprotein(a) combined with CatLet coronary score in predicting adverse events after emergency PCI for AMI patientsPLoS One · January 2026 3
• Association of lipoprotein(a), oxidized phospholipids and apolipoprotein B100 in acute ischemic stroke cohortAdv Lipoprotein A Res · January 2026 3