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2025 focused update of the 2019 ESC/EAS dyslipidaemia guidelines (Mach, Koskinas, Roeters van Lennep et al., EHJ 2025)

Original title: 2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias

Eur Heart J · · 8

Mach F, Koskinas KC, Roeters van Lennep JE, Tokgözoğlu L, Badimon L, Baigent C, Benn M, Binder CJ, Catapano AL, De Backer GG, Delgado V, Fabin N et al.

The European focused update, presented at ESC Congress 2025 in Madrid, revises the LDL-C pathway around earlier combination therapy and incorporates the new trial evidence; for lipoprotein(a) it keeps the once-in-a-lifetime measurement, positions Lp(a) as a risk modifier and states that no outcomes evidence for specific lowering yet exists. Jeanine Roeters van Lennep (Erasmus MC) is a task-force chair. See the guideline explainer videos in the Video section.

Read the paper (DOI)PubMed

Dutch researchguidelinestesting

Summary written by lp-a.org from the published abstract; figures as published. Page updated 17 August 2026. Methods.