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Two women with normal cholesterol and low coronary calcium scores still had significant coronary disease and high Lp(a), a case report (J Clin Lipidol 2020)

Original title: Coronary artery disease with normal lipids and low coronary artery calcium in two women with high lipoprotein(a)

J Clin Lipidol · · 4

Haxhi J, Pershwitz G, Thompson PD

This case report describes two women with elevated lipoprotein(a) [Lp(a)] and significant coronary artery disease despite normal lipid levels and low coronary artery calcium scores. The authors note clinicians should be aware that patients with elevated Lp(a) may have important coronary artery disease despite low coronary artery calcification scores, which are often used to reassure patients of low risk.

Read the paper (DOI)PubMed

Original abstract

We present 2 patients with elevated levels of lipoprotein (a) and significant coronary artery disease despite having little coronary artery calcification. Clinicians should be aware that patients with elevated lipoprotein (a) may have important coronary artery disease with low coronary artery calcification scores.

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Summary written by lp-a.org from the published abstract; figures as published. Page updated 18 August 2026. Methods.