GuidelinesLandmark

2018 AHA/ACC guideline on the management of blood cholesterol: Lp(a) as a risk-enhancing factor (Grundy et al., Circulation 2019)

Original title: 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Circulation · 18 June 2019 · 6

Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA et al.

The 2018 US cholesterol guideline (executive summary) introduced lipoprotein(a) of 50 mg/dL or 125 nmol/L or more as a risk-enhancing factor favouring statin initiation in intermediate-risk adults, and named a family history of premature ASCVD as a relative indication for measurement. Superseded by the 2026 guideline; kept here as the baseline the field moved from.

Read the paper (DOI)PubMed

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Summary written by lp-a.org from the published abstract; figures as published. Page updated 17 August 2026. Methods.